Benfica vs Bayer Leverkusen: Predictions, Betting odds, Lineups, Preview

Explore Bwin's detailed preview for Benfica vs Bayer Leverkusen in the UEFA Champions League. Stats, odds, predictions, and lineups for the 20:00 GMT match.

• Fixture: Benfica vs Bayer Leverkusen

• Date: Wednesday, 05 November 2025

• Kick-off: 20:00 GMT

• Venue: Estádio do Sport Lisboa e Benfica

Benfica's recent form suggests a team struggling to find the net, with three consecutive losses and only one win in their last five matches. Their defensive solidity, as seen in the clean sheet against Fenerbahce, could be crucial against a Bayer Leverkusen side that has shown vulnerability at the back, conceding seven goals to Paris Saint Germain. Benfica might look to exploit Leverkusen's defensive frailties while maintaining a tight defensive structure.

Bayer Leverkusen, despite a heavy defeat to PSG, has shown resilience in drawing against PSV Eindhoven and FC Copenhagen. Their attacking play could pose problems for a Benfica defense that has been breached multiple times recently. However, Leverkusen's inconsistent results might lead to a cautious approach, potentially resulting in a closely contested match.

Benfica's recent form has been poor, with three losses in their last five games, including heavy defeats to Newcastle and Chelsea. Their inability to score consistently, as evidenced by the 0-3 and 0-1 losses, could be a concern against a Bayer Leverkusen side that has shown some defensive weaknesses. However, their clean sheet against Fenerbahce at home suggests they can be solid defensively, which might help them in this match.

Loss: 0-3 vs Newcastle (A)

Loss: 0-1 vs Chelsea (A)

Loss: 2-3 vs Qarabag (H)

Win: 1-0 vs Fenerbahce (H)

Draw: 0-0 vs Fenerbahce (A)

Bayer Leverkusen's recent performances have been mixed, with a heavy loss to PSG but draws against PSV Eindhoven and FC Copenhagen. Their ability to score, as seen in the 2-2 draw against Copenhagen, indicates they can be dangerous going forward. However, the 7-2 defeat to PSG highlights potential defensive issues that Benfica might look to exploit.

• Loss: 2-7 vs Paris Saint Germain (H)

• Draw: 1-1 vs PSV Eindhoven (H)

• Draw: 2-2 vs FC Copenhagen (A)

The head-to-head record between Benfica and Bayer Leverkusen shows a mixed history, with their last encounter in 2014 ending in a 0-0 draw. Prior to that, Bayer Leverkusen secured a 3-1 victory over Benfica. This suggests that both teams have the potential to challenge each other, with neither having a clear dominance in their previous meetings.

• Benfica 0-0 Bayer Leverkusen (09 Dec 2014)

• Bayer Leverkusen 3-1 Benfica (01 Oct 2014)

• A. Bah (Knee Injury) - Out

• Bruma (Achilles Tendon Injury) - Out

• G. Prestianni (Inactive) - Out

• Manu (Knee Injury) - Out

• E. Palacios (Groin Injury) - Out

• M. Tillman (Muscle Injury) - Out

• N. Tella (Knee Injury) - Out

• A. Tape (Hamstring Injury) - Doubt

• Lucas (Muscle Injury) - Doubt

• Predicted lineup: Trubin (GK), Dedic (DF), Silva (DF), Otamendi (DF), Araujo (DF), Aursnes (DF), Lukebakio (MF), Rios (MF), Barrenechea (MF), Sudakov (MF), Pavlidis (AT)

Benfica's predicted lineup suggests a focus on defensive stability with Otamendi and Silva at the back, while Rios and Sudakov in midfield will be key to controlling the game's tempo and providing support to Pavlidis up front.

• Predicted lineup: Flekken (GK), Bade (DF), Tapsoba (DF), Andrich (MF), Arthur (MF), Fernandez (MF), Garcia (MF), Grimaldo (MF), Echeverri (MF), Poku (AT), Kofane (AT)

Bayer Leverkusen's predicted lineup indicates a balanced approach, with Bade and Tapsoba providing defensive solidity and Garcia and Echeverri in midfield expected to drive the team's attacking play.

• Pavlidis vs Bade: This duel will be crucial, with Pavlidis looking to exploit any gaps in Bade's defensive positioning to score for Benfica.
• Sudakov vs Echeverri: The midfield battle between Sudakov and Echeverri could determine which team gains control of the game's tempo and possession.
• Rios (Benfica): Rios's ability to control the midfield and distribute the ball effectively will be vital for Benfica's chances of winning.
• Garcia (Bayer Leverkusen): Garcia's creativity and goal-scoring threat from midfield could be the key to unlocking Benfica's defense.

Fans in the UK are able to watch Benfica vs Bayer Leverkusen on TNT Sports 6 at 20:00 GMT on Wednesday, 05 November 2025

Bwin is predicting that the score will be 1-1 in the match between Benfica and Bayer Leverkusen

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