FC Barcelona vs Olympiacos F.C.: Predictions, Betting odds, Lineups, Preview

Explore Bwin's detailed preview for FC Barcelona vs Olympiacos F.C. in the Champions League. Stats, odds, predictions, and lineups for the 17:45 BST match.

• Fixture: FC Barcelona vs Olympiacos F.C.

• Date: Tuesday, 21 October 2025

• Kick-off: 17:45 BST

• Venue: Camp Nou

Match Prediction: FC Barcelona 2-0 Olympiacos F.C.

FC Barcelona, coming off a mixed bag of results with a loss to Paris Saint Germain and a win against Newcastle United, will look to dominate possession and control the tempo against Olympiacos. Their recent form suggests a reliance on quick transitions and exploiting spaces, which could be effective against Olympiacos' more defensive setup seen in their draw against Pafos. Barcelona's attacking prowess, led by players like Rashford and Yamal, should test Olympiacos' backline.

Olympiacos, having struggled to score in their recent outings against Arsenal and Pafos, will likely adopt a counter-attacking strategy. Their resilience in defence, as shown in the goalless draw against Pafos, could pose challenges for Barcelona's forwards. However, Olympiacos' lack of offensive firepower might hinder their ability to capitalise on any opportunities they create.

Barcelona's recent form has been inconsistent, with a home loss to Paris Saint-Germain preceded by an away win against Newcastle United. The defeat against PSG highlighted vulnerabilities in their defence, which they will need to address against Olympiacos.

However, their victory over Newcastle showcased their ability to perform under pressure on the road, suggesting they can bounce back strongly. This mixed form could lead to a cautious approach, focusing on maintaining possession and minimising risks.

Recent Champions League Results:

• Loss: 1-2 vs Paris Saint-Germain (H)

• Win: 2-1 vs Newcastle United (A)

Olympiacos have struggled to find the net in their recent matches, drawing 0-0 with Pafos and losing 0-2 to Arsenal. Their inability to score against Pafos at home indicates a lack of offensive threat, which could be a significant disadvantage against a team like Barcelona.

Defensively, they showed resilience against Pafos, but their performance against Arsenal suggests they might struggle against stronger opposition. Olympiacos will need to be highly organised and disciplined to keep the scoreline respectable.

Recent Champions League Results:

• Loss: 0-2 vs Arsenal (A)

• Draw: 0-0 vs Pafos FC (H)

In their previous encounters, FC Barcelona have had the upper hand, winning 3-1 at home and drawing 0-0 away against Olympiacos. These results suggest Barcelona's dominance in this fixture, with their only recent blemish being the goalless draw. Olympiacos will need to overcome this historical disadvantage to achieve a favourable outcome in this match.

• Olympiacos F.C. 0-0 FC Barcelona (31 Oct 2017)

• FC Barcelona 3-1 Olympiacos F.C. (18 Oct 2017)

• Joan García (Meniscus) - Out

• Gavi (Arthroscopy) - Out

• Marc-André ter Stegen (Back) - Out

• Fermín López (Muscle) - Doubt

• Lamine Yamal (Groin) - Doubt

• Raphinha (Hamstring) - Doubt

• Dani Olmo (Unknown) - Doubt

• Roman Yaremchuk (Calf) - Doubt

• Konstantinos Angelakis (Unknown) - Doubt

• Panagiotis Retsos (Unknown) - Doubt

• Rodinei (Calf) - Doubt

• Gabriel Strefezza (Knock) - Doubt

• Mehdi Taremi (Unknown) - Doubt

• Predicted lineup: Szczesny, Koundé, E García, Cubarsí, Martin, De Jong, Pedri, Yamal (if fit), Olmo, Rashford, Torres

With Pedri and Frenkie de Jong in midfield, Barcelona will aim to control the game's tempo and dictate play. The inclusion of Rashford and Yamal (if fit) suggests a focus on quick, incisive attacks to break down Olympiacos' defence.

• Predicted lineup: Tzolakis, Costinha, Retsos, (if fit), Pirola, Ortega, Hezze, D García, Martins, Chiquinho, Podence, El Kaabi

Olympiacos' lineup, featuring El Kaabi and Podence, indicates a strategy focused on counter-attacks. Their midfield, anchored by Hezze and García, will need to be robust to disrupt Barcelona's rhythm and launch quick transitions.

• Lamine Yamal vs Francisco Ortega: This duel will see Barcelona's forward Yamal looking to exploit any space he can create against Ortega on Olympiacos' left flank.

• Pedri vs Chiquinho: The midfield battle between Barcelona's Pedri and Olympiacos' Chiquinho will be crucial in determining who controls the game's flow.

• Frenkie de Jong (FC Barcelona): Frenkie de Jong's ability to dictate the tempo and distribute the ball effectively makes him a pivotal player for Barcelona.

• Costinha (Olympiacos F.C.): Costinha's role in breaking up play and initiating counter-attacks is vital for Olympiacos' strategy against Barcelona.

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Odds and market details are accurate as of the time of publication.