Manchester City vs Bayer Leverkusen: Predictions, Betting odds, Lineups, Preview

Explore Bwin's detailed preview for Manchester City vs Bayer Leverkusen in the UEFA Champions League. Stats, odds, predictions, and lineups for the 20:00 GMT match.

• Fixture: Manchester City vs Bayer Leverkusen
• Date: Tuesday, 25 November 2025
• Kick-off: 20:00 GMT
• Venue: Etihad Stadium

Manchester City's recent form suggests a dominant performance against Bayer Leverkusen. With three wins and a draw in their last four matches, including a convincing 4-1 victory over Borussia Dortmund, City's attacking prowess is evident. Their ability to score multiple goals at home, as seen against Dortmund and Napoli, suggests they could exploit Leverkusen's defensive vulnerabilities, particularly after a heavy 7-2 loss to PSG.

Bayer Leverkusen, on the other hand, have been inconsistent, with a win, a loss, and two draws in their recent outings. Their narrow 1-0 victory over Benfica shows they can be resilient, but the 7-2 thrashing by PSG highlights significant defensive issues. Leverkusen might struggle to contain Manchester City's potent attack, potentially leading to a high-scoring game where City's superior form and home advantage could be decisive.

Manchester City's recent form has been impressive, with three wins and one draw in their last four matches. Their ability to secure victories both at home and away, including a 4-1 win against Borussia Dortmund and a 2-0 victory over Villarreal, showcases their consistency and strength. This form suggests they are likely to approach the game against Bayer Leverkusen with confidence, potentially leading to a strong performance.

Recent UEFA Champions League Results:

• Win: 4-1 vs Borussia Dortmund (H)
• Win: 2-0 vs Villarreal (A)
• Draw: 2-2 vs Monaco (A)
• Win: 2-0 vs Napoli (H)

Bayer Leverkusen's recent results have been mixed, with a win, a loss, and two draws in their last four games. Their 1-0 victory over Benfica indicates they can be competitive, but the 7-2 home defeat to PSG raises concerns about their defensive stability. This inconsistency could impact their performance against a formidable Manchester City side, potentially putting them at a disadvantage.

Recent UEFA Champions League Results:

• Win: 1-0 vs Benfica (A)

• Loss: 2-7 vs Paris Saint-Germain (H)

• Draw: 1-1 vs PSV Eindhoven (H)

• Draw: 2-2 vs FC Copenhagen (A)

Manchester City and Bayer Leverkusen have never faced each other in the Champions League, so punters will have to rely on the pair's respective recent form to make a judgment on who will come out on top.

• Mateo Kovacic (Ankle) - Out

• Arthur Augusto (Back) - Out

• Alejandro Grimaldo (Muscle) - Out

• Robert Andrich (Suspended) - Out

• Edmond Tapsoba (Suspended) - Out

• Axel Tape (Hamstring) - Out

• Exequiel Palacios (Adductor) - Out

• Lucas Vázquez (Muscle) - Out

• Equi Fernandez (Ligament) - Out

• Nathan Tella (Knee) - Doubt

• Ernest Poku (Knock) - Doubt

• Predicted lineup: Donnarumma (GK), Nunes (DF), Dias (DF), Gvardiol (DF), O'Reilly (DF), Nico (MF), Cherki (MF), Silva (MF), Foden (MF), Doku (MF), Haaland (AT)

Manchester City's predicted line-up suggests a focus on maintaining a solid defensive structure while leveraging their attacking options. With Haaland leading the line and supported by creative players like Foden and Doku, City's strategy will likely involve exploiting Leverkusen's defensive weaknesses.

• Predicted lineup: Flekken (GK), Belocian (DF), Bade (DF), Quansah (DF), Tella (MF)(If fit), Maza (MF), Garcia (MF), Hofmann (MF), Kofane (AT), Poku (AT)(If fit), Schick (AT)

Bayer Leverkusen's predicted line-up indicates a need to balance their defensive and offensive play. With Bade anchoring the defence and Schick leading the attack, Leverkusen will aim to be resilient at the back while looking for opportunities to counter-attack.

• Haaland vs Bade: This matchup will be crucial, with Haaland's goal-scoring prowess tested against Bade's defensive capabilities.

• Nico vs Garcia: The battle between Nico and Garcia could dictate the tempo and control of the game.

• Foden (Manchester City): Foden's creativity and ability to unlock defences make him a pivotal player for Manchester City's attacking strategy.

• Kofane (Bayer Leverkusen): Kofane's role as the main striker for Leverkusen will be vital in their efforts to score against a strong Manchester City defence.

Manchester City vs Bayer Leverkusen at 20:00 GMT on Tuesday, 25 November 2025, will be broadcast live for viewers in the UK on TNT Sports 1 and TNT Sports Ultimate.

Bwin is predicting that the score will be Manchester City 3-1 Bayer Leverkusen.

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For the best UEFA Champions League outright predictions, explore our guide.

Odds and market details are accurate as of the time of publication.