Napoli vs Eintracht Frankfurt: Predictions, Betting odds, Lineups, Preview

Explore Bwin's detailed preview for Napoli vs Eintracht Frankfurt in the UEFA Champions League. Stats, odds, predictions, and lineups for the 17:45 GMT match.

• Fixture: Napoli vs Eintracht Frankfurt

• Date: Tuesday, 04 November 2025

• Kick-off: 17:45 GMT

• Venue: Stadio Diego Armando Maradona

Napoli, despite recent inconsistent results, may leverage their home advantage to control the game's tempo. Their victory against Sporting CP suggests they can rebound from setbacks, potentially exploiting Eintracht Frankfurt's defensive vulnerabilities exposed in their heavy losses to Liverpool and Atletico Madrid. Napoli's midfield, with players like Politano and Gilmour, could dictate play and create scoring opportunities.

Eintracht Frankfurt, on the other hand, will need to recover from their recent poor form. Their sole win against Galatasaray indicates potential for offensive bursts, but their defence has been porous. Frankfurt might adopt a more cautious approach, looking to counter-attack and capitalise on any Napoli errors. The match could hinge on Frankfurt's ability to maintain discipline and exploit transitions.

Napoli's recent form has been a mix of highs and lows, with a significant loss to Manchester City followed by a home win against Sporting CP and another loss to PSV Eindhoven. This inconsistency might affect their confidence, but their home performance against Sporting CP shows they can be resilient. Napoli will need to focus on tightening their defence while utilising their midfield strength to control the game and create scoring chances.

• Loss: 0-2 vs Manchester City (A)

• Win: 2-1 vs Sporting CP (H)

• Loss: 2-6 vs PSV Eindhoven (A)

Eintracht Frankfurt's recent results have been predominantly negative, with heavy defeats to Liverpool and Atletico Madrid overshadowing their win against Galatasaray. This poor run of form could impact their morale, but their offensive display against Galatasaray suggests they have the capability to score. Frankfurt will need to shore up their defence and be more clinical in attack to stand a chance against Napoli.

• Win: 5-1 vs Galatasaray (H)

• Loss: 1-5 vs Atletico Madrid (A)

• Loss: 1-5 vs Liverpool (H)

Napoli has dominated their recent encounters with Eintracht Frankfurt, securing a 3-0 victory in their last meeting and a 2-0 win in the previous match. This head-to-head record suggests Napoli has a psychological edge over Frankfurt. However, past results do not guarantee future outcomes, and Frankfurt will be eager to overturn this record.

• Napoli 3-0 Eintracht Frankfurt (15 Mar 2023)

• Eintracht Frankfurt 0-2 Napoli (21 Feb 2023)

• A. Meret (Foot Injury) - Out

• A. Rrahmani (Thigh Injury) - Out

• David Neres (Injury) - Out

• K. De Bruyne (Injury) - Out

• R. Hojlund (Thigh Injury) - Out

• R. Lukaku (Thigh Injury) - Out

• S. Lobotka (Muscle Injury) - Doubt

• N. Contini (Hand Injury) - Doubt

• E. Baum (Thigh Injury) - Out

• O. Hojlund (Thigh Injury) - Out

• Predicted lineup: Milinkovic-Savic (GK), Lorenzo (DF), Beukema (DF), Buongiorno (DF), Spinazzola (DF), Politano (MF), Anguissa (MF), Gilmour (MF), McTominay (MF), Elmas (MF), Lucca (AT)

Napoli's predicted lineup suggests a focus on midfield control with Politano and Gilmour, aiming to dictate the game's pace and create scoring opportunities for Lucca.

• Predicted lineup: Zetterer (GK), Amenda (DF), Koch (DF), Theate (DF), Kristensen (MF), Gotze (MF), Larsson (MF), Brown (MF), Doan (AT), Knauff (AT), Bahoya (AT)

Eintracht Frankfurt's lineup suggests a reliance on counterattacks, with Kristensen and Gotze pivotal in transitioning from defence to attack, supporting the attacking trio of Doan, Knauff, and Bahoya.

• Lucca vs Koch: This duel will be crucial, with Lucca's attacking prowess tested against Koch's defensive solidity.
• Gilmour vs Larsson: Gilmour's ability to control the midfield will be challenged by Larsson's tenacity and work rate.
• Politano (Napoli): Politano's creativity and goal-scoring threat from midfield make him a vital player for Napoli's offensive strategy.
• Kristensen (Eintracht Frankfurt): Kristensen's role in transitioning play from defense to attack is essential for Frankfurt's counter-attacking approach.

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Odds and market details are accurate as of the time of publication.