Napoli vs Inter: Predictions, Betting odds, Lineups, Preview

Explore Bwin's detailed preview for Napoli vs Inter in the Serie A. Stats, odds, predictions, and lineups for the 17:00 BST match.

• Fixture: Napoli vs Inter

• Date: Saturday, 25 October 2025

• Kick-off: 17:00 BST

• Venue: Stadio Diego Armando Maradona Stadium

Match Prediction: Napoli 1-2 Inter

Napoli's recent form suggests a team capable of high-scoring victories at home but vulnerable on the road. Their attacking flair, evident in wins against Pisa and Fiorentina, could challenge Inter's defence, yet their losses to Torino and Milan indicate potential struggles against strong opposition. Inter, on the other hand, have shown consistent form with a strong defensive record, as seen in their wins against Roma, Cremonese, and Cagliari. The match may hinge on Inter's ability to exploit Napoli's defensive frailties while maintaining a solid backline against Napoli's potent attack.

The game could see Napoli pushing forward aggressively at home, aiming to replicate their scoring form against Pisa and Fiorentina. However, Inter's disciplined approach and recent success in tight games might allow them to control the tempo and capitalise on counter-attacks. Expect a closely contested match with both teams likely to score, but Inter's defensive solidity might just edge them ahead.

Napoli's recent performances have been a mix of high-scoring wins and disappointing losses. Their victories against Genoa, Pisa, and Fiorentina showcase their attacking prowess, which could be crucial against Inter. However, their away defeats to Torino and Milan highlight defensive vulnerabilities that Inter might exploit. Napoli will need to balance their offensive ambition with defensive discipline to secure a favourable result.

Recent Serie A Results:

• Loss: 0-1 vs Torino (A)
• Win: 2-1 vs Genoa (H)
• Loss: 1-2 vs Milan (A)
• Win: 3-2 vs Pisa (H)
• Win: 3-1 vs Fiorentina (A)

Inter have demonstrated a robust and consistent form, winning four out of their last five matches. Their ability to secure victories against strong teams like Roma and Cagliari, coupled with a high-scoring win against Cremonese, indicates a well-rounded squad. The only blemish, a loss to Juventus, suggests they can be challenged but remain a formidable force. Inter's defensive strength and tactical discipline could be key in navigating Napoli's home advantage.

Recent Serie A Results:

• Win: 1-0 vs Roma (A)
• Win: 4-1 vs Cremonese (H)
• Win: 2-0 vs Cagliari (A)
• Win: 2-1 vs Sassuolo (H)
• Loss: 3-4 vs Juventus (A)

The head-to-head record between Napoli and Inter shows a closely contested rivalry, with three draws in their last five encounters. Napoli's home win in May 2023 contrasts with a heavy defeat in December 2023, indicating the unpredictability of these matches. Both teams have shown they can score against each other, suggesting another competitive and potentially high-scoring game.

• Napoli 1-1 Inter (01 Mar 2025)
• Inter 1-1 Napoli (10 Nov 2024)
• Inter 1-1 Napoli (17 Mar 2024)
• Napoli 0-3 Inter (03 Dec 2023)
• Napoli 3-1 Inter (21 May 2023)

• Romelu Lukaku (Hamstring) - Out
• Stanislav Lobotka (Adductor) - Out
• Rasmus Hojlund (Muscle) - Doubt
• Scott McTominay (Ankle) - Doubt
• Amir Rrahmani (Hamstring) - Doubt
• Nikita Contini (Hand) - Doubt

• Raffaele Di Gennaro (Hand) - Out

• Marcus Thuram (Thigh) - Doubt

• Matteo Darmian (Muscle) - Doubt

• Predicted lineup: Milinković-Savić (GK), Di Lorenzo (DF), Beukema (DF), Jesus (DF), Olivera (DF), Gilmour (MF), Neres (MF), Anguissa (MF), De Bruyne (MF), Spinazzola (MF), Lucca (AT)

Napoli's predicted lineup suggests a focus on maintaining possession with Gilmour and De Bruyne in midfield, aiming to feed the ball to Lucca up front. Their recent form indicates a need for defensive solidity, which might be tested by Inter's attacking threats.

• Predicted lineup: Sommer (GK), Acerbi (DF), Akanji (DF), Bastoni (DF), Dumfries (MF), Barella (MF), Mkhitaryan (MF), Çalhanoğlu (MF), Dimarco (MF), Bonny (AT), Martínez (AT)

Inter's lineup emphasises a strong defensive core with Acerbi, Akanji, and Bastoni, aiming to neutralise Napoli's attack. The midfield trio of Çalhanoğlu, Mkhitaryan, and Barella will be crucial in controlling the game's tempo and supporting the forwards.

• Lorenzo Lucca vs Francesco Acerbi: This duel will be pivotal, with Napoli's powerful striker looking to outmaneuvre Inter's experienced defender.
• Frank Anguissa vs Hakan Çalhanoğlu: A battle in the midfield where Anguissa's skill and tenacity will be tested against Çalhanoğlu’s versatility and range of passing.
• Kevin De Bruyne (Napoli): His vision and passing ability make him a central figure in Napoli's midfield, crucial for orchestrating their attacks.
• Nicolo Barella (Inter): His dynamism and goal-scoring threat from midfield could be decisive for Inter's chances of winning.

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Odds and market details are accurate as of the time of publication.