RB Leipzig vs Bayer Leverkusen: Predictions, Betting odds, Lineups, Preview

Explore Bwin's detailed preview for RB Leipzig vs Bayer Leverkusen in the Bundesliga. Stats, odds, predictions, and lineups for the 17:30 GMT match.

• Fixture: RB Leipzig vs Bayer Leverkusen
• Date: Saturday, 20 December 2025
• Kick-off: 17:30 GMT
• Venue: Red Bull Arena

RB Leipzig's recent form suggests a team capable of high-scoring victories at home but vulnerable on the road. Their predicted 4-3-3 lineup, with the attacking trio of Bakayoko, Harder, and Gomis, indicates a strategy focused on exploiting the flanks and pressing high up the pitch. This approach could challenge Bayer Leverkusen's back three, especially if RB Leipzig can replicate their 6-0 thrashing of Eintracht Frankfurt.

Bayer Leverkusen, on the other hand, have shown inconsistency, with strong home performances but struggles away from home. Their 3-4-2-1 formation, featuring the creative duo of Tillman and Hofmann behind striker Schick (If fit), suggests a balanced approach that can switch between defensive solidity and quick counter-attacks. The head-to-head record indicates close contests, so expect a competitive match with both teams likely to score.

RB Leipzig's recent form has been a mix of highs and lows, with two convincing home wins but three losses on the road. Their 6-0 victory over Eintracht Frankfurt at home demonstrates their potential for dominant performances, while the 1-3 loss to Union Berlin away suggests vulnerabilities on the road. This inconsistency could impact their confidence, but their strong home record might give them the momentum needed for a positive result.

Recent Bundesliga Results:

• Loss: 1-3 vs Union Berlin (A)

• Win: 6-0 vs Eintracht Frankfurt (H)

• Draw: 0-0 vs Borussia Mönchengladbach (A)

• Win: 2-0 vs Werder Bremen (H)

• Loss: 1-3 vs 1899 Hoffenheim (A)

Bayer Leverkusen have shown a pattern of strong home form but struggles away, with two wins at home and two losses on the road in their recent matches. Their 6-0 home win against 1. FC Heidenheim highlights their ability to deliver high-scoring victories, while the 0-2 loss to FC Augsburg away indicates challenges in maintaining performance levels on the road. This form suggests they might be more confident playing at home, but need to address their away form.

Recent Bundesliga Results:

• Win: 2-0 vs 1. FC Köln (H)

• Loss: 0-2 vs FC Augsburg (A)

• Loss: 1-2 vs Borussia Dortmund (H)

• Win: 3-1 vs VfL Wolfsburg (A)

• Win: 6-0 vs 1. FC Heidenheim (H)

The head-to-head record between RB Leipzig and Bayer Leverkusen shows a pattern of closely contested matches, with the last five encounters resulting in high-scoring affairs. The last meeting ended in a 2-2 draw at the Red Bull Arena, with the previous meeting in Leverkusen ending in a 3-2 win for Leipzig.

The trend suggests both teams are capable of scoring, with four out of the last five matches featuring at least three goals, indicating a potential for another exciting and competitive game.

Recent Bundesliga Results

• RB Leipzig 2-2 Bayer Leverkusen (25 Jan 2025)

• Bayer Leverkusen 2-3 RB Leipzig (31 Aug 2024)

• RB Leipzig 2-3 Bayer Leverkusen (20 Jan 2024)

• Bayer Leverkusen 3-2 RB Leipzig (19 Aug 2023)

• Bayer Leverkusen 2-0 RB Leipzig (23 Apr 2023)

• Viggo Gebel (Knee) - Out

• Assan Ouédraogo (Hamstring) - Out

• Rômulo (Knee) - Out

• Ridle Baku (Ankle) - Out

• Antonio Nusa (Ankle) - Out

• Ezechiel Banzuzi (Hip) - Out

• Yan Diomande (International duty)

• Amadou Haidara (International duty)

• Benjamin Henrichs (Achilles) - Doubt

• Bitshiabu El Chadaille (Thigh) - Doubt

• Exequiel Palacios (Groin) - Out

• Lucas Vazquez (Muscle) - Out

• Alejandro Grimaldo (Mouth) - Out

• Ernest Poku (Hamstring) - Out

• Patrick Schick (Ankle) - Out

• Jarell Quansah (Suspended) - Out

• Christian Kofane (International duty) - Out

• Ibrahim Maza (International duty) - Out

• Edmond Tapsoba (International duty) - Out

• Eliesse Ben Seghir (International duty) - Out

• Predicted lineup: Gulacsi (GK), Nedeljkovic (DF), Orban (DF), Lukeba (DF), Raum (DF), Baumgartner (MF), Seiwald (MF), Schlager (MF), Bakayoko (AT), Harder (AT), Gomis (AT)

RB Leipzig's predicted 4-3-3 formation, with Gulacsi in goal and a back four of Nedeljkovic, Orban, Lukeba, and Raum, suggests a balanced approach between defence and attack. The midfield trio of Baumgartner, Seiwald, and Schlager will likely focus on controlling the game's tempo. Meanwhile, the attacking line of Bakayoko, Harder, and Gomis aims to exploit spaces and create scoring opportunities.

• Predicted lineup: Flekken (GK), Belocian (DF), Andrich (DF), Bade (DF), Arthur (MF), Garcia (MF), Fernández (MF), Tella (MF), Hofmann (AT), Tillman (AT), Schick (AT)(If fit)

Bayer Leverkusen's predicted 3-4-2-1 formation, anchored by Flekken in goal and a back three of Belocian, Andrich, and Bade, emphasises defensive solidity. The midfield quartet of Arthur, Garcia, Fernández, and Tella will support the attacking trio of Hofmann, Tillman, and Schick (If fit), suggesting a strategy that can switch between defensive resilience and quick, incisive attacks.

• Harder vs Bade: Harder's pace and movement will test Bade's defensive positioning and speed.

• Seiwald vs Garcia: Seiwald's midfield control will be crucial against Garcia's dynamic playmaking.

• Bakayoko (RB Leipzig): Bakayoko's ability to break through defences makes him a key threat for RB Leipzig.

• Tillman (Bayer Leverkusen): Tillman's creativity and vision in the final third are vital for Bayer Leverkusen's attack.

RB Leipzig vs Bayer Leverkusen at 17:30 GMT on Saturday, 20 December 2025, will be broadcast live for viewers in the UK on Sky Sports Football.

Bwin is predicting that the score will be RB Leipzig 2-1 Bayer Leverkusen.

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